N-glycosylation in the protease domain of trypsin-like serine proteases mediates calnexin-assisted protein folding
Trypsin-like serine proteases are essential in physiological processes. Studies have shown that N-glycans are important for serine protease expression and secretion, but the underlying mechanisms are poorly understood. Here, we report a common mechanism of N-glycosylation in the protease domains of...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2018-06-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/35672 |