Inferring interaction partners from protein sequences using mutual information.

Functional protein-protein interactions are crucial in most cellular processes. They enable multi-protein complexes to assemble and to remain stable, and they allow signal transduction in various pathways. Functional interactions between proteins result in coevolution between the interacting partner...

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Bibliographic Details
Main Author: Anne-Florence Bitbol
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-11-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC6258550?pdf=render