Clustering and Erratic Movement Patterns of Syringe-Injected versus Mosquito-Inoculated Malaria Sporozoites Underlie Decreased Infectivity

Malaria still causes a major burden on global health and the economy. The efficacy of live, attenuated malaria sporozoites as vaccine candidates critically depends on their ability to migrate to and infect the host liver.

Bibliographic Details
Main Authors: C. M. de Korne, B. M. F. Winkel, M. N. van Oosterom, S. Chevalley-Maurel, H. M. Houwing, J. C. Sijtsma, S. Azargoshasb, E. Baalbergen, B. M. D. Franke-Fayard, F. W. B. van Leeuwen, M. Roestenberg
Format: Article
Language:English
Published: American Society for Microbiology 2021-04-01
Series:mSphere
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00218-21