Study of potential xanthine oxidase inhibitors: In silico and in vitro biological activity

Study of potential xanthine oxidase inhibitors: In silico and in vitro biological activity

In an attempt to develop potent anti gout agents, coumarin derivatives and polyphenolic compounds were selected for present study. The docking energy of 2-benzyl coumarin was found to be -7.50 kcal/mol which was less than that of the standard allopurinol (-4.47 kcal/mol). All the selected compounds...

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Bibliographic Details
Main Authors: Muthuswamy Umamaheswari, Arumugam Madeswaran, Kuppusamy Asokkumar, Thirumalaisamy Sivashanmugam, Varadharajan Subhadradevi, Puliyath Jagannath
Format: Article
Language:English
Published: Bangladesh Pharmacological Society 2011-12-01
Series:Bangladesh Journal of Pharmacology
Subjects:
Allopurinol
AutoDock 4.2
Docking
Enzyme kinetics
Xanthine oxidase
Online Access:https://www.banglajol.info/index.php/BJP/article/view/9175

Internet

https://www.banglajol.info/index.php/BJP/article/view/9175

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