Lessons from Randomised Clinical Trials for Triiodothyronine Treatment of Hypothyroidism: Have They Achieved Their Objectives?

Randomised controlled trials are deemed to be the strongest class of evidence in evidence-based medicine. Failure of trials to prove superiority of T3/T4 combination therapy over standard LT4 monotherapy has greatly influenced guidelines, while not resolving the ongoing debate. Novel studies have re...

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Bibliographic Details
Main Authors: Rudolf Hoermann, John E. M. Midgley, Rolf Larisch, Johannes W. Dietrich
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Journal of Thyroid Research
Online Access:http://dx.doi.org/10.1155/2018/3239197