Risk of Hepatocellular Carcinoma after HCV Clearance by Direct-Acting Antivirals Treatment Predictive Factors and Role of Epigenetics

Risk of Hepatocellular Carcinoma after HCV Clearance by Direct-Acting Antivirals Treatment Predictive Factors and Role of Epigenetics

Direct-acting antivirals (DAAs) induce a rapid virologic response (SVR) in up to 99% of chronic hepatitis C patients. The role of SVR by DAAs on the incidence or recurrence of hepatocellular carcinoma (HCC) is still a matter of debate, although it is known that SVR does not eliminate the risk of HCC...

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Bibliographic Details
Main Authors: Luca Rinaldi, Riccardo Nevola, Gianluigi Franci, Alessandro Perrella, Giusy Corvino, Aldo Marrone, Massimiliano Berretta, Maria Vittoria Morone, Marilena Galdiero, Mauro Giordano, Luigi Elio Adinolfi, Ferdinando Carlo Sasso
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cancers
Subjects:
hepatocellular carcinoma
direct acting antivirals
HCV
cytokines
sustained virological response
epigenetic modulation
Online Access:https://www.mdpi.com/2072-6694/12/6/1351

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https://www.mdpi.com/2072-6694/12/6/1351

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