In silico characterisation of putative Plasmodium falciparum vaccine candidates in African malaria populations

Abstract Genetic diversity of surface exposed and stage specific Plasmodium falciparum immunogenic proteins pose a major roadblock to developing an effective malaria vaccine with broad and long-lasting immunity. We conducted a prospective genetic analysis of candidate antigens (msp1, ama1, rh5, eba1...

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Bibliographic Details
Main Authors: O. Ajibola, M. F. Diop, A. Ghansah, L. Amenga-Etego, L. Golassa, T. Apinjoh, M. Randrianarivelojosia, O. Maiga-Ascofare, W. Yavo, M. Bouyou-Akotet, K. M. Oyebola, B. Andagalu, U. D’Alessandro, D. Ishengoma, A. A. Djimde, E. Kamau, A. Amambua-Ngwa
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-95442-4