An autocrine sphingosine-1-phosphate signaling loop enhances NF-κB-activation and survival
<p>Abstract</p> <p>Background</p> <p>Sphingosine-1-phosphate (S1P) is a bioactive lipid that regulates a multitude of cellular functions, including cell proliferation, survival, migration and angiogenesis. S1P mediates its effects either by signaling through G protein-c...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-06-01
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Series: | BMC Cell Biology |
Online Access: | http://www.biomedcentral.com/1471-2121/11/45 |