An autocrine sphingosine-1-phosphate signaling loop enhances NF-κB-activation and survival

<p>Abstract</p> <p>Background</p> <p>Sphingosine-1-phosphate (S1P) is a bioactive lipid that regulates a multitude of cellular functions, including cell proliferation, survival, migration and angiogenesis. S1P mediates its effects either by signaling through G protein-c...

Full description

Bibliographic Details
Main Authors: Meinander Annika, Bergelin Nina, Blom Tomas, Löf Christoffer, Slotte J Peter, Eriksson John E, Törnquist Kid
Format: Article
Language:English
Published: BMC 2010-06-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/11/45