Distribution of HLA-DRB1 alleles in a mixed population with insulin-dependent diabetes mellitus from the Southeast of Brazil

Distribution of HLA-DRB1 alleles in a mixed population with insulin-dependent diabetes mellitus from the Southeast of Brazil

HLA class II genes are strongly associated with susceptibility and resistance to insulin-dependent diabetes mellitus (IDDM). The present study reports the HLA-DRB1 genotyping of 41 IDDM patients and 99 healthy subjects from the Southeast of Brazil (Campinas region). Both groups consisted of an ethni...

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Bibliographic Details
Main Authors: S.B.D. Marques, W. Volpini, S. Caillat-Zucman, S.R. Lieber, E.J. Pavin, L.B. Persoli
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 1998-03-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
insulin-dependent diabetes mellitus
genetic markers
DNA typing
HLA-DRB1
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000300005

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000300005

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