Bioinformatic analysis revealing mitotic spindle assembly regulated NDC80 and MAD2L1 as prognostic biomarkers in non-small cell lung cancer development

Bioinformatic analysis revealing mitotic spindle assembly regulated NDC80 and MAD2L1 as prognostic biomarkers in non-small cell lung cancer development

Abstract Background Lung cancer has been the leading cause of tumor related death, and 80% ~ 85% of it is non-small cell lung cancer (NSCLC). Even with the rising molecular targeted therapies, for example EGFR, ROS1 and ALK, the treatment is still challenging. The study is to identify credible respo...

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Bibliographic Details
Main Authors: Rong Wei, Ziyue Wang, Yaping Zhang, Bin Wang, Ningning Shen, Li E, Xin Li, Lifang Shang, Yangwei Shang, Wenpeng Yan, Xiaoqin Zhang, Wenxia Ma, Chen Wang
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Medical Genomics
Subjects:
Non-small cell lung cancer (NSCLC)
Lung adenocarcinoma (LUAD)
Squamous cell carcinoma (LUSC)
GEO database
TCGA data
Biomarker
Online Access:http://link.springer.com/article/10.1186/s12920-020-00762-5

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http://link.springer.com/article/10.1186/s12920-020-00762-5

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