Tamoxifen ameliorates peritoneal membrane damage by blocking mesothelial to mesenchymal transition in peritoneal dialysis.

Mesothelial-to-mesenchymal transition (MMT) is an auto-regulated physiological process of tissue repair that in uncontrolled conditions such as peritoneal dialysis (PD) can lead to peritoneal fibrosis. The maximum expression of peritoneal fibrosis induced by PD fluids and other peritoneal processes...

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Main Authors: Jesús Loureiro, Pilar Sandoval, Gloria del Peso, Guadalupe Gónzalez-Mateo, Vanessa Fernández-Millara, Beatríz Santamaria, Maria Auxiliadora Bajo, José Antonio Sánchez-Tomero, Gonzalo Guerra-Azcona, Rafael Selgas, Manuel López-Cabrera, Abelardo I Aguilera
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3634067?pdf=render