Infusion of HIV-1 Nef-expressing astrocytes into the rat hippocampus induces enteropathy and interstitial pneumonitis and increases blood-brain-barrier permeability.

Infusion of HIV-1 Nef-expressing astrocytes into the rat hippocampus induces enteropathy and interstitial pneumonitis and increases blood-brain-barrier permeability.

Even though HIV-1 replication can be suppressed by combination antiretroviral therapy (cART) inflammatory processes still occur, contributing to comorbidities. Comorbidities are attributed to variety of factors, including HIV-1 mediated inflammation. Several HIV-1 proteins mediate central nervous sy...

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Bibliographic Details
Main Authors: Jocelyn Rivera, Raymond A Isidro, Raisa Y Loucil-Alicea, Myrella L Cruz, Caroline B Appleyard, Angel A Isidro, Gladys Chompre, Krystal Colon-Rivera, Richard J Noel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0225760

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https://doi.org/10.1371/journal.pone.0225760

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