The Uremic Toxin Indoxyl Sulfate Accelerates Thrombotic Response after Vascular Injury in Animal Models

The Uremic Toxin Indoxyl Sulfate Accelerates Thrombotic Response after Vascular Injury in Animal Models

Chronic kidney disease (CKD) patients are at high risk for thrombotic events. Indoxyl sulfate (IS) is one of the most potent uremic toxins that accumulates during CKD. Even though IS is associated with an increased risk for cardiovascular disease, its impact on thrombotic events still remains not fu...

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Bibliographic Details
Main Authors: Malgorzata Karbowska, Tomasz W. Kaminski, Natalia Marcinczyk, Tomasz Misztal, Tomasz Rusak, Lukasz Smyk, Dariusz Pawlak
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Toxins
Subjects:
indoxyl sulfate
uremic toxin
thrombosis
hemostatic disorder
chronic kidney disease
prothrombotic state
cardiovascular event
tryptophan derivative
Online Access:https://www.mdpi.com/2072-6651/9/7/229

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https://www.mdpi.com/2072-6651/9/7/229

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