Establishing a stable, repeatable platform for measuring changes in sperm DNA methylation

Establishing a stable, repeatable platform for measuring changes in sperm DNA methylation

Abstract Background Several independent research groups have shown that alterations in human sperm methylation profiles correlate with decreased fecundity and an increased risk of poor embryo development. Moving these initial findings from the lab into a clinical setting where they can be used to me...

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Bibliographic Details
Main Authors: Mohammad Abbasi, Andrew D. Smith, Harish Swaminathan, Peer Sangngern, Amanda Douglas, Alan Horsager, Douglas T. Carrell, Philip J. Uren
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Clinical Epigenetics
Subjects:
DNA methylation
Epigenetics
Clinical Laboratory Improvement Amendments
CLIA
Laboratory-developed test
LDT
Online Access:http://link.springer.com/article/10.1186/s13148-018-0551-7

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http://link.springer.com/article/10.1186/s13148-018-0551-7

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