Therapeutic potential of the novel hybrid molecule JM-20 against focal cortical ischemia in rats

Therapeutic potential of the novel hybrid molecule JM-20 against focal cortical ischemia in rats

Context: Despite the great mortality and morbidity of stroke, treatment options remain limited. We previously showed that JM-20, a novel synthetic molecule, possessed a strong neuroprotective effect in rats subjected to transient middle cerebral artery occlusion. However, to verify the robustness of...

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Main Authors: Yanier Núñez Figueredo, Jeney Ramírez-Sanchez, Gisele Hansel, Gilberto L. Pardo-Andreu, Nelson Merino, Guillermo Aparicio, Rene Delgado-Hernández, Laura García-Pupo, Estael Ochoa-Rodríguez, Yamila Verdecia-Reyes, Diogo O. Souza
Format: Article
Language:English
Published: Academic Association of Pharmaceutical Sciences from Antofagasta (ASOCIFA) 2016-08-01
Series:Journal of Pharmacy & Pharmacognosy Research
Subjects:
Cerebral ischemia
cylinder test
JM-20
neuroprotection
thermocoagulation
Online Access:http://jppres.com/jppres/pdf/vol4/jppres16.126_4.4.153.pdf

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http://jppres.com/jppres/pdf/vol4/jppres16.126_4.4.153.pdf

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