CNV Radar: an improved method for somatic copy number alteration characterization in oncology

CNV Radar: an improved method for somatic copy number alteration characterization in oncology

Abstract Background Cancer associated copy number variation (CNV) events provide important information for identifying patient subgroups and suggesting treatment strategies. Technical and logistical issues, however, make it challenging to accurately detect abnormal copy number events in a cost-effec...

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Bibliographic Details
Main Authors: David Soong, Jeran Stratford, Herve Avet-Loiseau, Nizar Bahlis, Faith Davies, Angela Dispenzieri, A. Kate Sasser, Jordan M. Schecter, Ming Qi, Chad Brown, Wendell Jones, Jonathan J. Keats, Daniel Auclair, Christopher Chiu, Jason Powers, Michael Schaffer
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BMC Bioinformatics
Subjects:
Copy number variation
Next generation sequencing
Multiple myeloma
Acute myeloid leukemia
Prostate cancer
Online Access:http://link.springer.com/article/10.1186/s12859-020-3397-x

Internet

http://link.springer.com/article/10.1186/s12859-020-3397-x

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