Fms-Like Tyrosine Kinase 3-Independent Dendritic Cells Are Major Mediators of Th2 Immune Responses in Allergen-Induced Asthmatic Mice

Fms-Like Tyrosine Kinase 3-Independent Dendritic Cells Are Major Mediators of Th2 Immune Responses in Allergen-Induced Asthmatic Mice

Dendritic cells (DCs) are the main mediators of Th2 immune responses in allergic asthma, and Fms-like tyrosine kinase 3 ligand (Flt3L) is an important growth factor for the development and homeostasis of DCs. This study identified the DC populations that primarily cause the initiation and developmen...

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Bibliographic Details
Main Authors: Sang Chul Park, Dahee Shim, Hongmin Kim, Yeeun Bak, Da Yeon Choi, Joo-Heon Yoon, Chang-Hoon Kim, Sung Jae Shin
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
allergic asthma
dendritic cells
Fms-like tyrosine kinase 3
murine model
OX40 ligand
Th2 immune responses
Online Access:https://www.mdpi.com/1422-0067/21/24/9508

Internet

https://www.mdpi.com/1422-0067/21/24/9508

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