Membrane-anchored human Rab GTPases directly mediate membrane tethering in vitro

Rab GTPases are master regulators of eukaryotic endomembrane systems, particularly functioning in membrane tethering to confer the directionality of intracellular membrane trafficking. However, how exactly Rab GTPases themselves act upon membrane tethering processes has remained enigmatic. Here, we...

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Bibliographic Details
Main Authors: Naoki Tamura, Joji Mima
Format: Article
Language:English
Published: The Company of Biologists 2014-10-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/3/11/1108