Blockade of Experimental Multiple Sclerosis by Inhibition of the Acid Sphingomyelinase/Ceramide System

Blockade of Experimental Multiple Sclerosis by Inhibition of the Acid Sphingomyelinase/Ceramide System

Background: Multiple sclerosis (MS) is a severe and common autoimmune disorder of the central nervous system. Despite the availability of several novel treatment options, the disease is still poorly controlled, since the pathophysiological mechanisms are not fully understood. Methods: We tested the...

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Bibliographic Details
Main Authors: Katrin Anne Becker, Ramona Halmer, Laura Davies, Brian D. Henry, Regan Ziobro-Henry, Yann Decker, Yang Liu, Erich Gulbins, Klaus Fassbender, Silke Walter
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-11-01
Series:Neurosignals
Subjects:
Multiple sclerosis
Acid sphingomyelinase
Ceramide
Tight junctions
Experimental autoimmune encephalomyelitis
Online Access:https://www.karger.com/Article/FullText/484621

Internet

https://www.karger.com/Article/FullText/484621

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