The macrophage LBP gene is an LXR target that promotes macrophage survival and atherosclerosis

The macrophage LBP gene is an LXR target that promotes macrophage survival and atherosclerosis

The liver X receptors (LXRs) are members of the nuclear receptor superfamily that regulate sterol metabolism and inflammation. We sought to identify previously unknown genes regulated by LXRs in macrophages and to determine their contribution to atherogenesis. Here we characterize a novel LXR target...

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Bibliographic Details
Main Authors: Tamer Sallam, Ayaka Ito, Xin Rong, Jason Kim, Caroline van Stijn, Brian T. Chamberlain, Michael E. Jung, Lily C. Chao, Marius Jones, Thomas Gilliland, XiaoHui Wu, Grace L. Su, Rajendra K. Tangirala, Peter Tontonoz, Cynthia Hong
Format: Article
Language:English
Published: Elsevier 2014-06-01
Series:Journal of Lipid Research
Subjects:
nuclear receptor
atherogenesis
liver X receptor
lipopolysaccharide binding protein
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520352755

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http://www.sciencedirect.com/science/article/pii/S0022227520352755

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