Type I Interferon Receptor on NK Cells Negatively Regulates Interferon-γ Production

Type I Interferon Receptor on NK Cells Negatively Regulates Interferon-γ Production

NK cells are a key antiviral component of the innate immune response to HSV-2, particularly through their production of IFN-γ. It is still commonly thought that type I IFN activates NK cell function; however, rather than requiring the type I IFN receptor themselves, we have previously found that typ...

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Bibliographic Details
Main Authors: Amanda J. Lee, Firoz Mian, Sophie M. Poznanski, Michele Stackaruk, Tiffany Chan, Marianne V. Chew, Ali A. Ashkar
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Immunology
Subjects:
NK cells
type I IFN
IFN-γ
HSV
Human NK cells
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01261/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01261/full

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