Synthesis, Leishmanicidal and Cytotoxic Activity of Triclosan-Chalcone, Triclosan-Chromone and Triclosan-Coumarin Hybrids
Twelve hybrids derived from triclosan were obtained via Williamson etherification of O-triclosan alkyl bromide plus chalcone and O-coumarin or O-chromone alkyl bromide plus triclosan, respectively. Structures of the products were elucidated by spectroscopic analysis. The synthesized compounds were e...
Main Authors: | Elver Otero, Sebastián Vergara, Sara M. Robledo, Wilson Cardona, Miguel Carda, Ivan D. Vélez, Carlos Rojas, Felipe Otálvaro |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2014-08-01
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Series: | Molecules |
Subjects: | |
Online Access: | http://www.mdpi.com/1420-3049/19/9/13251 |
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