Type II NKT cells stimulate diet-induced obesity by mediating adipose tissue inflammation, steatohepatitis and insulin resistance.

Type II NKT cells stimulate diet-induced obesity by mediating adipose tissue inflammation, steatohepatitis and insulin resistance.

The progression of obesity is accompanied by a chronic inflammatory process that involves both innate and acquired immunity. Natural killer T (NKT) cells recognize lipid antigens and are also distributed in adipose tissue. To examine the involvement of NKT cells in the development of obesity, C57BL/...

Full description

Bibliographic Details
Main Authors: Masashi Satoh, Yasuhiro Andoh, Christopher Stuart Clingan, Hisako Ogura, Satoshi Fujii, Koji Eshima, Toshinori Nakayama, Masaru Taniguchi, Noriyuki Hirata, Naoki Ishimori, Hiroyuki Tsutsui, Kazunori Onoé, Kazuya Iwabuchi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3284453?pdf=render

Internet

http://europepmc.org/articles/PMC3284453?pdf=render

Similar Items