Astaxanthin Protects Primary Hippocampal Neurons against Noxious Effects of Aβ-Oligomers

Increased reactive oxygen species (ROS) generation and the ensuing oxidative stress contribute to Alzheimer’s disease pathology. We reported previously that amyloid-β peptide oligomers (AβOs) produce aberrant Ca2+ signals at sublethal concentrations and decrease the expression of type-2 ryanodine re...

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Bibliographic Details
Main Authors: Pedro Lobos, Barbara Bruna, Alex Cordova, Pablo Barattini, Jose Luis Galáz, Tatiana Adasme, Cecilia Hidalgo, Pablo Muñoz, Andrea Paula-Lima
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2016/3456783