Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality.

Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality.

Fibroblastic reticular cells (FRCs) form the cellular scaffold of lymph nodes (LNs) and establish distinct microenvironmental niches to provide key molecules that drive innate and adaptive immune responses and control immune regulatory processes. Here, we have used a graph theory-based systems biolo...

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Bibliographic Details
Main Authors: Mario Novkovic, Lucas Onder, Jovana Cupovic, Jun Abe, David Bomze, Viviana Cremasco, Elke Scandella, Jens V Stein, Gennady Bocharov, Shannon J Turley, Burkhard Ludewig
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-07-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.1002515

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https://doi.org/10.1371/journal.pbio.1002515

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