Adolescent stress increases depression-like behaviors and alters the excitatory-inhibitory balance in aged mice

Abstract. Background:. Depression affects approximately 5% of elderly people and its etiology might be related to chronic stress exposure during neurodevelopmental periods. In this study, we examined the effects of adolescent chronic social stress in aged mice on depressive behaviors and the excitat...

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Bibliographic Details
Main Authors: Hong-Li Wang, Ya-Xin Sun, Xiao Liu, Han Wang, Yu-Nu Ma, Yun-Ai Su, Ji-Tao Li, Tian-Mei Si, Li-Shao Guo
Format: Article
Language:English
Published: Wolters Kluwer 2019-07-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000000313