Matrix Metalloproteinases Retain Soluble FasL-mediated Resistance to Cell Death in Fibrotic-Lung Myofibroblasts

Matrix Metalloproteinases Retain Soluble FasL-mediated Resistance to Cell Death in Fibrotic-Lung Myofibroblasts

A prominent feature of obstructed tissue regeneration following injury in general, and fibrotic lung tissue in particular, is fibroblast proliferation and accumulation. The Fas/FasL apoptotic pathway has been shown to be involved in human idiopathic pulmonary fibrosis (IPF) and bleomycin-induced lun...

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Bibliographic Details
Main Authors: David Nareznoi, Jenya Konikov-Rozenman, Dmytro Petukhov, Raphael Breuer, Shulamit B. Wallach-Dayan
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cells
Subjects:
pulmonary fibrosis
lung myofibroblasts
matrix metalloproteinase (mmp)
soluble fasl (sfasl)
cell death
Online Access:https://www.mdpi.com/2073-4409/9/2/411

Internet

https://www.mdpi.com/2073-4409/9/2/411

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