IL-27 Derived From Macrophages Facilitates IL-15 Production and T Cell Maintenance Following Allergic Hypersensitivity Responses

IL-27 Derived From Macrophages Facilitates IL-15 Production and T Cell Maintenance Following Allergic Hypersensitivity Responses

Crosstalk between T cells, dendritic cells, and macrophages in temporal leukocyte clusters within barrier tissues provides a new concept for T cell activation in the skin. Activated T cells from these leukocyte clusters play critical roles in the efferent phase of allergic contact hypersensitivity (...

Full description

Bibliographic Details
Main Authors: Jutamas Suwanpradid, Min Jin Lee, Peter Hoang, Jeffery Kwock, Lauren P. Floyd, Jeffrey S. Smith, Zhinan Yin, Amber R. Atwater, Sudarshan Rajagopal, Ross M. Kedl, David L. Corcoran, Jennifer Y. Zhang, Amanda S. MacLeod
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
contact hypersensitivity
human allergic contact dermatitis
IL-27
IL-15
dermal leukocyte cluster
BCL2
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.713304/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.713304/full

Similar Items