Changes in CREB activation in the prefrontal cortex and hippocampus blunt ethanol-induced behavioral sensitization in adolescent mice

Changes in CREB activation in the prefrontal cortex and hippocampus blunt ethanol-induced behavioral sensitization in adolescent mice

Drug dependence is a major health problem in adults and has been recognized as a significant problem in adolescents. We previously demonstrated that repeated treatment with a behaviorally sensitizing dose of ethanol in adult mice induced tolerance or no sensitization in adolescents and that repeated...

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Bibliographic Details
Main Authors: Sabrina Lucio Soares-Simi, Daniel Mazzeo Pastrello, Zulma Silva Ferreira, Mauricio eYonamine, Tania eMarcourakis, Cristoforo eScavone, Rosana eCamarini
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Integrative Neuroscience
Subjects:
Adolescent
CREB-Binding Protein
Mice
behavioral sensitization
EMSA
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnint.2013.00094/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnint.2013.00094/full

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