Epistatic Interplay between Type IV Secretion Effectors Engages the Small GTPase Rab2 in the Brucella Intracellular Cycle

Epistatic Interplay between Type IV Secretion Effectors Engages the Small GTPase Rab2 in the Brucella Intracellular Cycle

Bacterial pathogens with an intracellular lifestyle modulate many host cellular processes to promote their infectious cycle. They do so by delivering effector proteins into host cells via dedicated secretion systems that target specific host functions. While the roles of many individual effectors ar...

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Bibliographic Details
Main Authors: Erin P. Smith, Alexis Cotto-Rosario, Elizabeth Borghesan, Kiara Held, Cheryl N. Miller, Jean Celli
Format: Article
Language:English
Published: American Society for Microbiology 2020-03-01
Series:mBio
Subjects:
brucella
rab2
type iv secretion
epistasis
macrophage
pathogenesis
Online Access:https://doi.org/10.1128/mBio.03350-19

Internet

https://doi.org/10.1128/mBio.03350-19

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