Dynamic Expressions of TIGIT on Splenic T Cells and TIGIT-Mediated Splenic T Cell Dysfunction of Mice With Chronic Toxoplasma gondii Infection

As an immunosuppressive receptor, T-cell immunoglobulin and immunoreceptor tyrosine-based inhibitory motif domain (TIGIT) play a critical part in cellular immune regulation mediated by pathogen infection. Whereas, TIGIT expression on splenic T cells in hosts infected with Toxoplasma gondii cysts has...

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Bibliographic Details
Main Authors: Haoran Li, Jing Zhang, Changwei Su, Xiaowei Tian, Xuefang Mei, Zhenchao Zhang, Mingyong Wang, Xiangrui Li, Shuai Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Microbiology
Subjects:
TEM
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.700892/full