Engineering CAR-T cells

Abstract Chimeric antigen receptor redirected T cells (CAR-T cells) have achieved inspiring outcomes in patients with B cell malignancies, and are now being investigated in other hematologic malignancies and solid tumors. CAR-T cells are generated by the T cells from patients’ or donors’ blood. Afte...

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Bibliographic Details
Main Authors: Cheng Zhang, Jun Liu, Jiang F. Zhong, Xi Zhang
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Biomarker Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40364-017-0102-y