Cyanidin suppresses amyloid beta-induced neurotoxicity by inhibiting reactive oxygen species-mediated DNA damage and apoptosis in PC12 cells

Cyanidin suppresses amyloid beta-induced neurotoxicity by inhibiting reactive oxygen species-mediated DNA damage and apoptosis in PC12 cells

Amyloid beta (Aß)-induced oxidative stress is a major pathologic hallmark of Alzheimer′s disease. Cyanidin, a natural flavonoid compound, is neuroprotective against oxidative damage-mediated degeneration. However, its molecular mechanism remains unclear. Here, we investigated the effects of cyanidin...

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Bibliographic Details
Main Authors: Yi Wang, Xiao-ting Fu, Da-wei Li, Kun Wang, Xin-zhi Wang, Yuan Li, Bao-liang Sun, Xiao-yi Yang, Zun-cheng Zheng, Nam Chun Cho
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; cyanidin; amyloid-beta; oxidative damage; reactive oxide species; apoptosis; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2016;volume=11;issue=5;spage=795;epage=800;aulast=Wang

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2016;volume=11;issue=5;spage=795;epage=800;aulast=Wang

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