Significance of microRNA targeted estrogen receptor in male fertility

Objective(s): Estrogen receptor-alpha (ERα) mediates estrogen action in regulation of different levels of the hypothalamic-pituitary-testis axis. It has a key role in spermatogenesis. Estrogen receptor alpha knock-out (ER koα) male mice were infertile and severe impairment in spermatogenesis and sem...

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Bibliographic Details
Main Authors: alireza abhari, Nosratollah Zarghami, Vahideh Shahnazi, Abolfazl Barzegar, Laya Farzadi, Hadi Karami, Sepideh Zununi Vahed, Mohammad Nouri
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2014-02-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:http://ijbms.mums.ac.ir/pdf_2238_0b74da452f548caea22002396a9e609d.html