CD4+CD25hiFOXP3+ Regulatory T Cells and Cytokine Responses in Human Schistosomiasis before and after Treatment with Praziquantel.

CD4+CD25hiFOXP3+ Regulatory T Cells and Cytokine Responses in Human Schistosomiasis before and after Treatment with Praziquantel.

BACKGROUND:Chronic schistosomiasis is associated with T cell hypo-responsiveness and immunoregulatory mechanisms, including induction of regulatory T cells (Tregs). However, little is known about Treg functional capacity during human Schistosoma haematobium infection. METHODOLOGY:CD4+CD25hiFOXP3+ ce...

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Main Authors: Yvonne Schmiedel, Ghyslain Mombo-Ngoma, Lucja A Labuda, Jacqueline J Janse, Brechje de Gier, Ayôla A Adegnika, Saadou Issifou, Peter G Kremsner, Hermelijn H Smits, Maria Yazdanbakhsh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4546370?pdf=render

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http://europepmc.org/articles/PMC4546370?pdf=render

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