MicroRNA-449a overexpression, reduced NOTCH1 signals and scarce goblet cells characterize the small intestine of celiac patients.

MicroRNA-449a overexpression, reduced NOTCH1 signals and scarce goblet cells characterize the small intestine of celiac patients.

MiRNAs play a relevant role in regulating gene expression in a variety of physiological and pathological conditions including autoimmune disorders. MiRNAs are also important in the differentiation and function of the mouse intestinal epithelium. Our study was aimed to look for miRNA-based modulation...

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Bibliographic Details
Main Authors: Marina Capuano, Laura Iaffaldano, Nadia Tinto, Donatella Montanaro, Valentina Capobianco, Valentina Izzo, Francesca Tucci, Giancarlo Troncone, Luigi Greco, Lucia Sacchetti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3240641?pdf=render

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http://europepmc.org/articles/PMC3240641?pdf=render

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