Microglia Mediate Synaptic Material Clearance at the Early Stage of Rats With Retinitis Pigmentosa

Microglia Mediate Synaptic Material Clearance at the Early Stage of Rats With Retinitis Pigmentosa

Resident microglia are the main immune cells in the retina and play a key role in the pathogenesis of retinitis pigmentosa (RP). Many previous studies on the roles of microglia mainly focused on the neurotoxicity or neuroprotection of photoreceptors, while their contributions to synaptic remodeling...

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Bibliographic Details
Main Authors: Juncai He, Congjian Zhao, Jiaman Dai, Chuan Huang Weng, Bai Shi Jiao Bian, Yu Gong, Lingling Ge, Yajie Fang, Hui Liu, Haiwei Xu, Zheng Qin Yin
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
microglia
synapse
rod bipolar cell
retinitis pigmentosa
ectopic neuritogenesis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00912/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00912/full

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