Spectrophotometric determination of cefaclor in pharmaceutical preparations

A simple spectrophotometric method is proposed for the determination of cefaclor. The method involves alkaline hydrolysis of the drug in ammonia buffer solution at pH 10 to yield diketopiperazine-2,5-dione derivative and subsequent measurement at 340 nm. Beer's law is obeyed in the concentratio...

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Bibliographic Details
Main Authors: Viviane M. Ivama, Letícia N. C. Rodrigues, Cláudia C. I. Guaratini, Maria Valnice B. Zanoni
Format: Article
Language:English
Published: Sociedade Brasileira de Química 1999-04-01
Series:Química Nova
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40421999000200011