Asynchrony between virus diversity and antibody selection limits influenza virus evolution

Seasonal influenza viruses create a persistent global disease burden by evolving to escape immunity induced by prior infections and vaccinations. New antigenic variants have a substantial selective advantage at the population level, but these variants are rarely selected within-host, even in previou...

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Bibliographic Details
Main Authors: Dylan H Morris, Velislava N Petrova, Fernando W Rossine, Edyth Parker, Bryan T Grenfell, Richard A Neher, Simon A Levin, Colin A Russell
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-11-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/62105