Recombination hotspots and population structure in Plasmodium falciparum.

Understanding the influences of population structure, selection, and recombination on polymorphism and linkage disequilibrium (LD) is integral to mapping genes contributing to drug resistance or virulence in Plasmodium falciparum. The parasite's short generation time, coupled with a high cross-...

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Bibliographic Details
Main Authors: Jianbing Mu, Philip Awadalla, Junhui Duan, Kate M McGee, Deirdre A Joy, Gilean A T McVean, Xin-zhuan Su
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-10-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC1201364?pdf=render