Aspirin-triggered lipoxin A<sub>4 </sub>attenuates LPS-induced pro-inflammatory responses by inhibiting activation of NF-κB and MAPKs in BV-2 microglial cells

<p>Abstract</p> <p>Background</p> <p>Microglial activation plays an important role in neurodegenerative diseases through production of nitric oxide (NO) and several pro-inflammatory cytokines. Lipoxins (LXs) and aspirin-triggered LXs (ATLs) are considered to act as ...

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Bibliographic Details
Main Authors: Yuan Shi-Ying, Zhou Jie-Ping, Liu Ren-Gang, Zheng Jin, Li Long-Yan, Wu Yan, Wang Yan-Ping, Shang You, Yao Shang-Long
Format: Article
Language:English
Published: BMC 2011-08-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/8/1/95