Prediction of conversion from mild cognitive impairment to dementia with neuronally derived blood exosome protein profile

Prediction of conversion from mild cognitive impairment to dementia with neuronally derived blood exosome protein profile

Abstract Introduction Levels of Alzheimer's disease (AD)‐related proteins in plasma neuronal derived exosomes (NDEs) were quantified to identify biomarkers for prediction and staging of mild cognitive impairment (MCI) and AD. Methods Plasma exosomes were extracted, precipitated, and enriched fo...

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Bibliographic Details
Main Authors: Charisse N. Winston, Edward J. Goetzl, Johnny C. Akers, Bob S. Carter, Edward M. Rockenstein, Douglas Galasko, Eliezer Masliah, Robert A. Rissman
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
Neuron
Exosomes
Mild cognitive impairment
Alzheimer's disease
Biomarker
Phospho‐tau
Online Access:https://doi.org/10.1016/j.dadm.2016.04.001

Internet

https://doi.org/10.1016/j.dadm.2016.04.001

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