Molecular Dynamics Simulation, Characterization and In Vitro Drug Release of Isoniazid Loaded Poly-ε-caprolactone Magnetite Nanocomposite

Molecular Dynamics Simulation, Characterization and In Vitro Drug Release of Isoniazid Loaded Poly-ε-caprolactone Magnetite Nanocomposite

Background: This study reports on the development of a controlled-release isoniazid (INH) drug delivery system using poly-є-caprolactone (PCL) functionalized magnetite-nanoparticles (MNPs), as a theoretical potential tool for tuberculosis (TB) chemotherapy. Method: The magnetite Fe3O4 core was fabri...

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Bibliographic Details
Main Authors: Aram dokht khatibi Khatibi, Zarrin Eshaghi, Hamid Mosaddeghi, Davoud Balarak
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2020-12-01
Series:Pharmaceutical Sciences
Subjects:
drug delivery
magnetite nanoparticles
poly-є-caprolactone
isoniazid
tuberculosis
molecular dynamics simulation
Online Access:https://ps.tbzmed.ac.ir/PDF/ps-26-406.pdf

Internet

https://ps.tbzmed.ac.ir/PDF/ps-26-406.pdf

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