Investigation of regioselectivity on the reaction of 5-bromo-2,4-dichloro-6-methylpyrimidine with ammonia

Regioselective displacement reaction of ammonia with 5-bromo-2,4-dichloro-6-methylpyrimidine was studied by X-ray crystallography analysis and showed the formation of 5-bromo-2-chloro-6-methylpyrimidin-4-amine as a main product. Reaction of the latter compound with secondary amines in boiling ethano...

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Bibliographic Details
Main Authors: Abdolhassan Doulah, Hossein Eshtiagh-Hosseini, Masoud Mirzaei, Mohsen Nikpour, Ali Fazlara, Ali R. Salimi
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:Arabian Journal of Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S187853521000290X