Brain-Derived Neurotrophic Factor Precursor in the Hippocampus Regulates Both Depressive and Anxiety-Like Behaviors in Rats

Depression and anxiety are two affective disorders that greatly threaten the mental health of a large population worldwide. Previous studies have shown that brain-derived neurotrophic factor precursor (proBDNF) is involved in the development of depression. However, it is still elusive whether proBDN...

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Bibliographic Details
Main Authors: Feng Zhong, Lei Liu, Jia-Li Wei, Zhao-Lan Hu, Li Li, Shuang Wang, Jun-Mei Xu, Xin-Fu Zhou, Chang-Qi Li, Zhao-Yun Yang, Ru-Ping Dai
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2018.00776/full