Brain-Derived Neurotrophic Factor Precursor in the Hippocampus Regulates Both Depressive and Anxiety-Like Behaviors in Rats
Depression and anxiety are two affective disorders that greatly threaten the mental health of a large population worldwide. Previous studies have shown that brain-derived neurotrophic factor precursor (proBDNF) is involved in the development of depression. However, it is still elusive whether proBDN...
Main Authors: | Feng Zhong, Lei Liu, Jia-Li Wei, Zhao-Lan Hu, Li Li, Shuang Wang, Jun-Mei Xu, Xin-Fu Zhou, Chang-Qi Li, Zhao-Yun Yang, Ru-Ping Dai |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-01-01
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Series: | Frontiers in Psychiatry |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fpsyt.2018.00776/full |
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