Clustering analysis of microRNA and mRNA expression data from TCGA using maximum edge-weighted matching algorithms

Abstract Background microRNA (miRNA) is a short RNA (~ 22 nt) that regulates gene expression at the posttranscriptional level. Aberration of miRNA expressions could affect their targeting mRNAs involved in cancer-related signaling pathways. We conduct clustering analysis of miRNA and mRNA using expr...

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Bibliographic Details
Main Authors: Lizhong Ding, Zheyun Feng, Yongsheng Bai
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Medical Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12920-019-0562-z