Monitoring early response to anti-angiogenic therapy: diffusion-weighted magnetic resonance imaging and volume measurements in colon carcinoma xenografts.

OBJECTIVES: To evaluate the use of diffusion-weighted MRI (DW-MRI) and volume measurements for early monitoring of antiangiogenic therapy in an experimental tumor model. MATERIALS AND METHODS: 23 athymic nude rats, bearing human colon carcinoma xenografts (HT-29) were examined before and after 6 day...

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Bibliographic Details
Main Authors: Moritz Jörg Schneider, Clemens Christian Cyran, Konstantin Nikolaou, Heidrun Hirner, Maximilian F Reiser, Olaf Dietrich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4164617?pdf=render