Cholinergic modulation of disorder-relevant human defensive behaviour in generalised anxiety disorder

Cholinergic modulation of disorder-relevant human defensive behaviour in generalised anxiety disorder

Abstract Drugs that are clinically effective against anxiety disorders modulate the innate defensive behaviour of rodents, suggesting these illnesses reflect altered functioning in brain systems that process threat. This hypothesis is supported in humans by the discovery that the intensity of threat...

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Bibliographic Details
Main Authors: Adam Perkins, Fiona Patrick, Toby Wise, Nicholas Meyer, Ndaba Mazibuko, Alice E. Oates, Anne H. M. van der Bijl, Philippe Danjou, Susan M. O’Connor, Elizabeth Doolin, Caroline Wooldridge, Deborah Rathjen, Christine Macare, Steven C. R. Williams, Allan H. Young
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-020-01141-5

Internet

https://doi.org/10.1038/s41398-020-01141-5

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