Intracellular Delivery of DNA and Protein by a Novel Cell-Permeable Peptide Derived from DOT1L

Cellular uptake and intracellular release efficiency of biomacromolecules is low because of hurdles in the cell membrane that result in limited access to intra-cellular targets with few functional effects. Cell-penetrating peptides (CPPs) act as cargo delivery vehicles to promote therapeutic molecul...

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Bibliographic Details
Main Authors: Jingping Geng, Xiangli Guo, Lidan Wang, Richard Q. Nguyen, Fengqin Wang, Changbai Liu, Hu Wang
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/10/2/217